Abstract: Interstitial radioactive particles implantation from close range from the initial treatment of prostate cancer to the treatment of multiple organ tumors, in clinical practice, perfect in technology continues to mature, has obtained the good curative effect, become a routine method in tumor treatment. In the process of its continuous development, the progress of imaging for assessment of tumor biological behavior played a vital role. With the progress of the operation of standardization and template technology, puncture accuracy improvement, particle source personalized development, treatment planning system implantation dose calculation and postoperative evaluation of the significance of the particles is become a new issue to promote the development of particle implantation. Organizations close radioactive particles implantation tumor treatment technology is a multidisciplinary cooperation edge discipline, the progress of any one discipline will bring new understanding of treatment.