18F-FDG PET心肌代谢显像在心肌存活诊断中的应用进展

Development of 18F-FDG PET myocardial metabolic imaging in the diagnosis of myocardial survival

  • 摘要: 严重冠状动脉疾病是左心室功能受损的主要原因,治疗效果不佳。许多冠脉造影显示,冠脉严重狭窄者治疗后心功能并无明显改善,仅部分患者从中受益。因此,有效评估心肌存活状态对冠脉血管重建术的选择和疗效预测有重要价值。核素心肌显像作为一种非侵入性检查,在冠心病诊断、危险度分层、缺血评估、预后判断等方面有重要作用,特别是18F-FDG PET心肌代谢显像,能够准确评估心肌的存活状态及比例,对冠心病的转归及治疗后的效果起着非常重要的作用。

     

    Abstract: Severe coronary artery disease is the cause of left ventricular dysfunction, and the treatment for this disease is not effective. Many coronary angiographies showed that severe coronary stenosis did not significantly improve heart function after treatment, except for a few patients. Therefore, effective assessment of the myocardial viability status for the coronary revascularization choice and efficacy has significant predictive value. Nuclide myocardial imaging as a noninvasive examination plays an important role in the diagnosis of coronary heart disease, risk stratification, ischemia assessment, prognosis, and so on. 18F-FDG PET imaging of myocardial metabolism can accurately assess the status and proportion of myocardial viability and possesses an important role in the outcome of coronary heart disease and the effect of treatment.

     

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