Abstract: Gastroesophageal reflux(GER) is a common digestive system disease with high incidence in infants and children. The long-term serious GER may provoke serious complications, early accurate detection of GER is crucial for its treatment. Milk scan gastroesophageal imaging is a kind of examination method which is mainly used for GER, gastric emptying, aspiration and the research on pathogenesis of GER. The clinical application is wide, but its specificity and sensitivity is low. At present, the application and research about milk scan is less in our country. This article mainly summarized the technology and clinical application and progression of milk scan.