Objective To observe the short-term efficacy of percutaneous lung puncture implantation of ¹²⁵I seeds guided by CT in the treatment of advanced lung cancer.

Methods Percutaneous lung puncture implantation of ¹²⁵I seeds were performed in 20 cases of advanced lung cancer patients. The short-term efficacy was observed according to the imaging results, and the complications were also followed.

Results According to the CT images, 15%(3/20) were complete remission in 20 cases implanted ¹²⁵I seeds for more than 3 months, and 55%(11/20) were partial remission, 30%(6/20) were no remission, 15%(3/20) were concurrent pneumothorax, 20%(4/20) coughed a few bloody sputum. The total effective rate was 70%. The follow-up time ranged from 3 to 18 months. 1 case died of respiratory failure 5 months after surgery.

Conclusion Implantation of ¹²⁵I seeds in the treatment of advanced lung cancer showed few complications and a satisfactory short-term efficacy, while the long-term efficacy was to be observed.