Abstract: Thyroid nodules was a common clinical disease. There are many characteristic imaging techniques used for the detection and characterization of thyroid nodules, including ultrasound, radionuclide imaging, MRI, CT and PET/CT. This article reviewed advanced research of the imaging techniques which mentioned above. Comparing the performance of these imaging techniques, ultrasound has been the prefer imaging technique in the diagnosis of thyroid nodules. Meanwhile using other imaging examinations can provide more informations for clinic.