Abstract: Coronary artery diseases are common complications for diabetic patients. Silent myocardial ischemia is a type of coronary artery disease which was usually occult in onset and asymptomatic that can be easily ignored, causing severe cardiovascular events. Therefore, it′s necessary to screen myocardial ischemia in such patients. SPECT myocardial perfusion imaging plays an important role in screening, diagnosing and predicting myocardial ischemia in diabetic patients as a noninvasive imaging technique.