Abstract: Nasopharyngeal carcinoma(NPC), which has high morbidity, difficult diagnosis, and poor treatment results, is a type of malignant tumor in head and neck cancer. The mainstay treatment for nasopharyngeal carcinoma has been radiotherapy as NPC is sensitive to radiotherapy. However, there is a significant rate of local failures and distant metastases. PET/CT, an important imaging modality in modern medicine, combines the functional imaging of PET and the anatomic imaging of CT to efficiently image tumor proliferation, metabolism, hypoxia and cell apoptosis. It can also precisely image the anatomic structure of tumors and their adjacent organs or tissues. PET/CT was found to be particularly helpful for guiding diagnosis and therapy, the staging and grading of tumors, monitoring therapy and in evaluating the prognosis of patients with nasopharyngeal carcinoma.