良恶性肿瘤18F-FDG符合线路显像的临床价值

18F-FDG coincidence imaging for the detection of benign and malignant neoplasm

    摘要
  • 摘要:
    目的 评价18F-FDG符合线路显像检测良恶性肿瘤的诊断价值。
    方法 回顾性分析135例病变性质不明患者的18F-FDG符合线路显像结果，并与常规影像学检查结果进行对比分析。病变的确诊依据手术病理检查和临床随诊。
    结果 135例患者经病理学检查及随访结果最终确诊为恶性病变者86例（病灶数：95个），良性病变者49例（病灶数：53个）。恶性病变中，18F-FDG检查病灶数较常规影像学检查增多38个，而病灶数减少的仅有8个。18F-FDG符合线路显像诊断恶性肿瘤的灵敏度、特异度和准确率分别为：90.7%（78/86）、87.8%（43/49）和89.6%（121/135）。
    结论 18F-FDG符合线路显像能更灵敏、准确地检出良恶性肿瘤，可为患者选择治疗方案提供可靠的依据。

     

    Abstract:
    Objective To evaluate 18F-FDG coincidence imaging for the detection of benign and malignant tumor diagnosis.
    Methods Retrospectively analyzing 13518F-FDG dual head coincidence imaging results whose patients had unknown lesions, and comparing with conventional radiographic examination results.The diagnosis of lesion is based on surgical pathology and clinical follow-up.
    Results Eighty-six of all the 135 patients were diagnosed as malignant lesions(of 95 niduses), 49 of all the cases were benign lesion (of 53 niduses).18F-FDG coincidence imaging detected 38 more niduses than conventional radiographic examination, where the niduses reduced by only eight.The sensitivity, specificity and accuracy of the 18FFDG coincidence imaging in diagnosing carcinoma were 90.7%(78/86), 87.8%(43/49)and 89.6%(121/ 135).
    Conclusion 18F-FDG coincidence imaging is more sensitive, accurate in detecting benign and malignant tumor, and helps to clinical diagnosing and selecting patients to provide reliable basis for treatment options.

     

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