99Tcm-DTPA肾动态显像测定肾小球滤过率的影响因素分析

Research on the influencing factors of measuring glomerular filtration rate through 99Tcm-DTPA renal dynamic imaging

  • 摘要: 肾小球滤过率(GFR)是反映肾功能的重要指标,利用99Tcm-二亚乙基三胺五乙酸(99Tcm-DTPA)进行肾动态显像检测GFR是目前临床最常用的方法,但测量过程中的一些可变因素和操作细节,如血浆蛋白结合、肾脏和本底感兴趣区勾画、肾脏深度、患者年龄及自身肾功能、患者准备情况和操作技术等,都可能对GFR的检测产生影响。该文对上述影响因素逐一进行分析、探讨,以期为临床工作提供一定参考。

     

    Abstract: Glomerular filtration rate(GFR)is an important criterion to estimate renal function.The most common way to measure GFR clinically is 99Tcm-DTPA Renal Dynamic Imaging.However, the result may be influenced by many factors such as plasma protein binding, delineation of kidney and background region of interest, kidney depth, age and renal function and preparation of patient, nurse's operative technique, etc.The article analyzed each factor above respectively for clinical reference.

     

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