Abstract: Hyperparathyroidism(HPT)is overactivity of the parathyroid glands resulting in excess production of parathyroid hormone.Excessive parathyroid hormone secretion may be due to problems in the glands themselves, or may be secondary HPT.The diagnosis is mainly based on the patient's medical history and biochemical tests.The best treatment nowadays is surgical removal of the overactive parathyroid glands or adenoma.The imaging methods for the preoperative localization diagnosis include radionuclide imaging, ultrasonography, CT, MRI, etc.This article was a summary of HPT radionuclide imaging.