Abstract: Metastatic spine tumors(MST)can occur in many primary malignant tumors, but X-ray cannot find early metastatic disease; CT scans can not directly show abnormity of the spinal marrow; MRI need a long time, patients with spinal tumors can hardly to be suffered which will affect image quality.Conventional bone scan has the ability to scan the entire skeleton, but the specificity is not high.However, the sensitivity and specificity can be improved about the diagnosis of MST by bone SPECT imaging, the distribution of the anatomical structure or morphology of the metastatic spinal tumors can be clearly displayed.PET-CT could detect the metastases of spine and other parts of the body sensitively and accurately, primary tumors that were unknown before examination could be found at the same time.This paper describes the diagnostic value of radionuclide bone scintigraphy of MST.