鼻咽癌在全身骨显像鼻部感兴趣区放射性异常的分析

Study on nasal radioactive anomalies of nasopharyngeal carcinoma in bone imaging

    摘要
  • 摘要:
    目的 研究全身骨显像中各类患者鼻部ROI放射性异常。
    方法 对712例临床诊断为鼻咽癌或疑似鼻咽癌的患者和1036例其他受检者用99Tcm-亚甲基二膦酸行全身骨显像，勾画其鼻部ROI，并分为6组（A~F组），对ROI每像素放射性计数最大值、ROI每像素放射性计数平均值、ROI每像素放射性计数平均值与本底对照区每像素放射性计数平均值的比值做统计学分析。
    结果 A组ROI每像素放射性计数平均值比F组低（t=3.47，P < 0.01），B、C、E三组比F组高（tA=17.73, tB= 4.39, tE=2.85，P均 < 0.01）。B、C两组ROI每像素放射性计数平均值与本底对照区平均值的比值显著高于F组（t=24.99, t=13.11，P均 < 0.01）。
    结论 临床怀疑或确诊为鼻咽癌或有其他鼻部肿瘤病史的检查者、有明确良恶性肿瘤病史的检查者，较一般检查者鼻部放射性明显增高。通过分析鼻部ROI数据可更早、更准确发现骨显像中鼻部的异常。

     

    Abstract:
    Objective To investigate radioactive abnormalities of nasopharyngeal carcinoma(NPC)in the bone imaging.
    Methods Divide 712 diagnosed or suspected NPC patients and other 1036 patients in 99Tcmmethylene diphosphonate bone imaging into 6 groups.Draw ROI of nasal region, and then analysis radioactive counts of ROI.
    Results Average radioactivity counts of A group were lower than F group(t=3.47, P < 0.01), and B, C and E groups higher than F group.It showed a significantly statistical difference(tA=17.73, tB=4.39, tE= 2.85, P < 0.01).The ratio of the average radioactivity counts per pixel and the background radioactivity counts of B and C groups were significantly higher than F group(t=24.99, t=13.11, P < 0.01).
    Conclusion Radioactivecounts of nasal part in diagnosed or suspected NPC and other carcinoma of nasal patients and the patients with the history of benign or malignant carcinoma increased significantly.

     

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