18F-FDG SPECT-CT在宫颈癌监测中的价值

The value of 18F-FDG SPECT-CT in detecting recurrence or metastasis of cervical cancer

    摘要
  • 摘要:
    目的 评价18F-FDG SPECT-CT在监测宫颈癌复发和(或)转移中的价值。
    方法 回顾性分析为评估宫颈癌是否复发和(或)转移而行18F-FDG SPECT-CT的62例患者的临床资料，以二次手术或局部活检病理或临床随访为最终结果，并与同期CT和鳞状细胞癌抗原(SCCA) 检查结果对比。
    结果 经病理或临床随访证实，62例患者中有36例复发和(或)转移。18F-FDG SPECT-CT对宫颈癌复发和(或)转移监测的灵敏度、特异度、阳性预测值、阴性预测值及准确率分别为94.4%、92.3%、94.4%、92.3%、93.5%；CT分别为69.4%、80.8%、83.3%、65.6%、74.2%；SCCA检查分别为66.7%、46.2%、63.2%、50.0%、58.1%。
    结论 18F-FDG SPECT-CT监测宫颈癌复发和(或)转移有较大临床价值。

     

    Abstract:
    Objective To evaluate the value of 18F-fluorodeoxyglucose(18F-FDG)SPECT-CT in detecting recurrence and(or) metastasis of cervical cancer.
    Methods Retrospective analysis of 62 patients who underwent 18F-FDG SPECT-CT to evaluate recurrence and/or metastasis of cervical cancer at Fujian Tumor Hospital. The diagnostic results were confirmed by second surgery, biopsy or clinical follow-up, and also compared with the coincidence images obtained by CT scan and the serum squamous cell carcinoma related antigen(SCCA) levels.
    Results It is confirmed that 36 of 62 patients had recurrence and(or) meta-stasis of cervical cancer by biopsy or clinical follow-up. The sensitivity, specificity, positivity predicitive value (PPV), negative predictive value (NPV), and accuracy of 18F-FDG SPECT-CT were 94.4%, 92.3, 94.4%, 92.3%and 93.5%. Those of CT scan were 69.4%, 80.8%, 83.3%, 65.6% and 74.2%. Those of SCCA measurement were 66.7%, 46.2%, 63.2%, 50.0% and 58.1%.
    Conclusions 18F-FDG SPECT-CT has greater clinical value to monitor recurrence and(or) metastasis of cervical cancer.

     

    • HTML全文
    • 参考文献(9)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回