股骨头无菌坏死弥散加权成像的临床应用

Clinical application of diffusion-weighted imaging in the femoral head necrosis patients

    摘要
  • 摘要:
    目的 对股骨头无菌性坏死（FHN）患者的磁共振弥散加权成像（DWI）的影像学特征进行总结分析，为FHN的诊断提供依据。
    方法 对22名股骨头正常者及42例FHN患者的磁共振信号分布及表观弥散系数（ADC）进行分析比较。
    结果 股骨头正常者T1加权像及T2加权像呈均匀高信号，DWI为低信号；FHN患者的T1加权像呈低信号和稍低信号，T2加权像呈不均匀高信号和稍高信号，DWI呈不均匀高信号。股骨头正常者、FHN患者病变周围区和中央区的ADC分别为（0.000~0.036）×10-3mm2/s、（0.111~0.311）×10-3mm2/s和（0.845~1.397）×10-3mm2/s，三者间的差异具有统计学意义（F＝1384.28，P < 0.05）。
    结论 FHN患者的DWI信号分布及ADC与股骨头正常者相比，具有明显的特异性，可用于对FHN患者的明确诊断，并可根据ADC的测量对骨髓病变进行量化分析。

     

    Abstract:
    Objective To summarize and analyze the imaging features of diffusion-weighted imaging (DWI)in femoral head necrosis(FHN)patients and provide the basis for the diagnosis of FHN.
    Methods The magnetic resonance signal distribution and apparent diffusion coefficient(ADC)in 22 normal person and 42 FHN patients were analyzed and compared.
    Results The homogeneous high signal was showed in T1WI and T2WI imaging for normal person and low signal in DWI.The slightly low and low signal in T1WI, the high signal and slightly inhomogeneous signal in T2WI and the heterogeneous high signal in DWI were showed for FHN patients.The ADC normal value of normal person, the around area and central area of FHN patients were(0.000-0.036)×10-3mm2/s, (0.111-0.311)×10-3mm2/s and(0.845-1.397)×10-3mm2/s respectively, there was statistically significant difference among three areas(F=1384.28, P < 0.05).
    Conclusion There is specificity in DWI signal distribution and ADC normal value in FHN patients compared with normal person.DWI can be used for the diagnosis of FHN patients and the ADC value can be used for quantify analysis of bone marrow lesions.

     

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