Abstract: Objective To discuss the iconography experience and feature of cerebral venous sinus and vein thrombosis(CVST). Methods To analyze the iconography manifestation and diagnosis feature of 28 CVST patients retrospectively. Results (1) The "cord-like" imaging, which is the typical direct sign,only can be seen in a few of CT and MRI iconography of CVST patients(3.57%).The most common indirect sign is atypical cerebral hemorrhage(50.00%) and cerebral infarction(CT:32.14%, MRI:39,29%). The most common diseased site is bilateral(75.00%).(2) Most of CT venography(CTV) or magnetic resonance angiography venography(MRV) of CVST patients show the direct sign, which include the continuity of the cerebral venous sinus was interrupted, filling defect and completely or worm-eaten-like changes(CTV:100%,MRV:83.33%), and the indirect sign, which include the thickening of the distal venous sinus and the expansion of the draining vein. Conclusions There is no significant specificity in CT and MRI imaging of CVST patients, while the CTV and MRV images show high specificity. The MRV or CTV should be executed early to confirmed diagnosis if the patient is suspected of suffering from CVST.