Abstract: The occurrence and development of esophgeal cancer is a result of many factors that effect each other, which involved disorders of multiple genes and levels of molecular. The application of ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) PET detecting tumor cells glucose uptaked is more and more generally in the tumor diagnosis, staging, curative effect evaluation, and prognosis judgement and so on, glucose transporter-1 has an important role in the esophgeal cancer cells glucose uptaked and cells proliferation process.