螺旋采集模式提高99Tcm-MIBI SPECT心肌灌注显像图像质量的临床研究

Clinical study of spiral acquisition mode to improve the image quality of 99Tcm-MIBI SPECT myocardial perfusion imaging

    摘要
  • 摘要:
    目的 探讨螺旋采集（Swiftscan）模式对99Tcm-甲氧基异丁基异腈（MIBI） SPECT心肌灌注显像（MPI）图像质量的影响。
    方法 采用横断面研究设计，回顾性分析2024年2月至6月于内蒙古自治区人民医院接受99Tcm-MIBI静息和负荷SPECT MPI的34例可疑及明确诊断为冠状动脉粥样硬化性心脏病的患者的临床资料和影像资料，其中男性23例、女性11例，中位年龄60岁。比较Swiftscan SPECT模式与传统步进式（SS）采集模式2组间MPI图像质量参数，包括左心室室壁边缘锐利度侧壁心外膜边界上计数减少的最大斜率（slope）、左心室室壁厚度半高峰宽度（FWHM）、对比度噪声比（CNR）、信噪比（SNR）及左心室17个节段心肌血流灌注评分百分比。Swiftscan和SS 2组间slope、FWHM、CNR、SNR及左心室17个节段心肌血流灌注评分百分比的比较采用Wilcoxon秩和检验；采用Bland-Altman法评估2组间左心室17个节段心肌灌注评分百分比的一致性。
    结果 Swiftscan组室壁边缘锐利度（slope）明显高于SS组0.012（0.004, 0.025）对0.006（0.001, 0.016），Z=−3.30, P<0.05；Swiftscan组的FWHM高于SS组7.87（7.03, 20.11） mm对7.52（6.93, 19.59） mm，Z=−2.17，P<0.05；Swiftscan组的CNR和SNR明显高于SS组7.90（6.45, 8.78）对6.48（5.50, 8.25）和27.95（23.06, 41.47）对22.19（16.89, 28.78），Z=−2.09、−3.00，均P<0.05。左心室17个节段心肌血流灌注评分百分比在2种采集模式下的差异均无统计学意义（Z=−1.92~−0.02，均P>0.05）；Bland-Altman法分析结果显示，2种采集模式下的左心室17个节段心肌灌注评分百分比具有很好的一致性，二者之间的偏倚为3.52（95%CI：−6.81~7.01）。
    结论 Swiftscan模式可明显提高99Tcm-MIBI SPECT MPI的图像质量。

     

    Abstract:
    Objective To investigate the effect of spiral acquisition (Swiftscan) mode on the image quality of 99Tcm-sestamibi (MIBI) SPECT myocardial perfusion imaging (MPI).
    Methods A cross-sectional study design was employed and a retrospective analysis was conducted on the clinical and imaging data of 34 patients with suspected or confirmed coronary artery disease who underwent both rest and stress 99Tcm-MIBI SPECT MPI at the Inner Mongolia Autonomous Region People's Hospital from February to June 2024. The patients included 23 males and 11 females, with a median age of 60 years. Compared the MPI image quality parameters between the Swiftscan SPECT mode and the traditional step-to-shoot (SS) acquisition mode groups. These parameters compared between the two groups were: the sharpness of the left ventricular wall edge (maximum slope of count reduction on the sidewall epicardial boundary (slope) ), left ventricular wall thickness (full width at half maximum (FWHM) ), contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), and the percentage of the 17-segment of left ventricular myocardial perfusion score. The Wilcoxon rank-sum test was used to compare the slope, FWHM, CNR, SNR, and the percentage of the 17-segment of left ventricular myocardial perfusion score between the Swiftscan and SS groups. Bland-Altman analysis was employed to assess the agreement in the percentage of the 17-segment of left ventricular myocardial perfusion score.
    Results The sharpness of the left ventricular wall edge in the Swiftscan group was significantly higher than that in the SS group (0.012(0.004, 0.025) vs. 0.006(0.001, 0.016), Z=−3.30, P<0.05). The FWHM in the Swiftscan group was higher than that in the SS group (7.87(7.03, 20.11) mm vs. 7.52(6.93, 19.59) mm, Z=−2.17, P<0.05). The CNR and SNR in the Swiftscan group were also significantly higher than those in the SS group (7.90(6.45, 8.78) vs. 6.48(5.50, 8.25) and 27.95(23.06, 41.47) vs. 22.19(16.89, 28.78), Z=−2.09, −3.00; all P<0.05). No statistically significant differences were observed in the percentage of the 17-segment of left ventricular myocardial perfusion score between the two acquisition modes (Z=−1.92 to −0.02, all P>0.05). Bland-Altman analysis demonstrated good agreement in the percentage of the 17-segment of left ventricular myocardial perfusion score between the two acquisition modes, with a bias of 3.52(95%CI: −6.81 to 7.01).
    Conclusion The Swiftscan acquisition mode can significantly improve the quality of 99Tcm-MIBI SPECT MPI images.

     

    • HTML全文
    • 参考文献(20)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回