18F-FDG PET/CT在泡型棘球蚴病代谢活性分析中的研究进展

Research progress of 18F-FDG PET/CT in the metabolic activity analysis of alveolar echinococcosis

  • 摘要: 泡型棘球蚴病(AE)是一种由多房棘球蚴的幼虫感染人体后引起的严重损害健康甚至危害生命的寄生虫病,常引发肝脏和其他脏器的严重破坏,由于早期不典型的临床症状及侵袭性的生长方式,AE的早期诊断及治疗面临挑战。近年来,18F-氟脱氧葡萄糖(FDG)PET/CT作为一种非侵入性的分子影像技术,在AE生物学代谢活性分析中取得了一定的进展。笔者对18F-FDG PET/CT在AE生物学特征方面的研究现状进行综述,重点关注了其在感染区域的代谢活性变化以及在治疗效果评估方面的应用。

     

    Abstract: Alveolar echinococcosis (AE) is an intense and potentially life-threatening parasitic infection resulting from the invasion of the larval form of the tapeworm echinococcus multilocularis. It often leads to extensive damage to the liver and other organs. Due to its early atypical clinical symptoms and invasive growth patterns, the early diagnosis and treatment of this disease pose significant challenges. In recent years, 18F-fluorodeoxyglucose (FDG) PET/CT has emerged as a non-invasive molecular imaging that has made significant strides in the biological activity analysis of AE. The authors provided a review of the current status of research on the biological characteristics of AE using 18F-FDG PET/CT, with a focus on its applications in assessing metabolic changes in infected regions and evaluating treatment outcomes.

     

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