Abstract: Nasopharyngeal carcinoma is a malignant tumor prevalent in China and Southeast Asian countries, characterized by a high recurrence and metastasis rate. Clinically, ¹⁸F-fluorodeoxyglucose (FDG) PET/CT imaging and monitoring of biochemical indicators have become indispensable components of the management of patients with nasopharyngeal carcinoma. The combined use of ¹⁸F-FDG PET/CT and inflammatory markers may have significant potential in improving the accuracy of nasopharyngeal carcinoma diagnosis and personalized treatment. This combination also plays a crucial role in enhancing the clinical prognosis of nasopharyngeal carcinoma patients. The authors systematically reviewed the application progress of ¹⁸F-FDG PET/CT parameters and inflammatory markers in predicting the prognosis of nasopharyngeal carcinoma patients.