Abstract: Stomach neoplasm is one of the most common malignant tumor of the digestive system, with a poor prognosis. Accurate qualitative diagnosis and staging are of great value for the formulation of treatment plans for gastric cancer. Radionuclide imaging such as PET/CT or PET/MR can perform in vivo imaging of tumors at the molecular or cellular level, thereby providing important information in the diagnosis, staging, restaging and therapeutic efficacy evaluation of gastric cancer. As some limitations of the conventional positron tracer ¹⁸F-FDG in gastric cancer applications still exist, a variety of novel molecular probes have been developed for gastric cancer diagnosis. In this paper, the current clinical application and research progress of PET/CT molecular imaging probes in the diagnosis of gastric cancer are reviewed.