Abstract: Plutonium emits α particles, which is one of the main occupational hazard factors for workers in nuclear fuel reprocessing. When evaluating the detriment of internal exposure caused by plutonium entering the body and the effect of decorporation, it is necessary to estimate the internal irradiation dose. The identification of the transfer and metabolism of plutonium in vivo is the basis for the estimation of internal exposure dose. In this paper, the current models related to plutonium transfer metabolism and their studies are reviewed, in order to provide reference for biokinetic research on plutonium.