Abstract: In order to correctly implement the Beijing local standard DB11/T 1930—2021 Quality control specification for tests of chromosome aberration and micronucleus in radiation workers' health examinations, and better guide the cytogenetic testing for radiation workers in health examination institutions, the background, main basis and main technical content of the standard were interpreted. This standard was formulated on the basis of extensive research on domestic and foreign literature, in accordance with relevant laws and regulations, national and industry standards, and on the basis of extensive consultation with peer experts . The basic requirements, laboratory and equipment requirements, and quality control for the test process of chromosomal aberrations and micronucleus in human peripheral blood lymphocytes during the health examination of radiation workers were specified in this standard. The interpretation of the standard can be used to guide the genetic laboratory of the occupational health examination institution of radiation workers to work in a more standardized and scientific way, and better ensure the safety and health of the radiation workers.