Abstract: Left ventricular assist device (LVAD) implantation is an important and effective method for the treatment of patients with end-stage heart failure. Infection is the most common complication. Delayed diagnosis or inadequate evaluation will lead to reduced survival and other serious consequences. In recent years, ¹⁸F-fluorodeoxyglucose(FDG) PET/CT plays an unique and important clinical effect in the diagnosis, location, classification, degree evaluation, treatment guidance and prognosis prediction of infection after LVAD implantation. The paper reviews the progress of clinical application of ¹⁸F-FDG PET/CT in infection after LVAD implantation.