Abstract: The authors reported a case of hydroa vacciniforme-like lymphoproliferative disorder (HVLPD) of ¹⁸F-fluorodeoxyglucose (FDG) PET/CT imaging. HVLPD is rare in clinic. At present, there are few cases reported in the literature about HVLPD ¹⁸F-FDG PET/CT imaging and efficacy evaluation. The characteristics of HVLPD were analysed according to clinical symptoms, laboratory examinations and ¹⁸F-FDG PET/CT imaging. The therapeutic effect of patients was evaluated in order to deepen clinicians' understanding of HVLPD.