颈动脉粥样硬化斑块内血管化和出血的影像学研究进展

Imaging research progress of intraplaque vascularization and hemorrhage in carotid atherosclerotic plaques

  • 摘要: 斑块内出血是动脉粥样硬化斑块不稳定的主要因素之一,斑块内出血的诊断对于颈动脉斑块患者的正确分期、治疗以及预防缺血性脑卒中至关重要。组织病理学检查是评价斑块内出血的“金标准”,但需要通过颈动脉内膜切除术来收集组织样本。然而,影像检查可作为一种非侵入性的方法来检测斑块内出血。笔者就颈动脉粥样硬化斑块内血管化和斑块内出血在超声、CT、MRI和核医学等方面的主要特点和发展前景进行综述。

     

    Abstract: Intraplaque hemorrhage is one of the main factors involved in atherosclerotic plaque instability. The diagnosis of intraplaque hemorrhage is very important for the correct staging, treatment and prevention of ischemic stroke in patients with carotid plaque. Histopathological examination is the "gold standard" to evaluate intraplaque haemorrhage, but it required carotid endarterectomy surgery to collect the tissue sample. Therefore, imaging examination can be used as a non-invasive method to detect intraplaque haemorrhage. This paper reviews the main characteristics and development prospects of intraplaque vascularization and intraplaque haemorrhage in ultrasound, computed tomography, magnetic resonance and nuclear medicine.

     

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