Abstract: The incidence of differentiated thyroid carcer (DTC) is increasing year by year. When distant metastasis occurs, the patients' life quality and survival rate were significantly reduced. Lung is the most common site, accounting for 55%-85% of distant metastasis with DTC, and is the main factor of death threat of thyroid cancer. Therefore, early diagnosis, evaluation and treatment decisions for these patients are particularly important, and it is also the key to shorten the gap between the diagnosis and treatment of thyroid cancer in China and developed countries and improve the quality of life of patients. This paper reviews the research progress in the epidemiological and clinic pathologic features, diagnosis, evaluation and treatment of pulmonary metastasis with DTC.