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淀粉样变是由不溶性纤维蛋白在细胞外沉积引起的一组疾病。根据分类依据的不同,可分为全身性和局限性、遗传性和获得性、原发性和继发性等类型,继发性淀粉样变多继发于肿瘤、类风湿性关节炎、干燥综合征或其他自身免疫性疾病[1]。淀粉样变可累及全身多个器官,常见的发病部位包括心脏、肝脏、肾脏、肺和皮肤等,目前国内外对其报道较少。
双肺多发结节性淀粉样变18F-FDG PET/CT显像一例
18F-FDG PET/CT imaging of double lung multiple nodular amyloidosis: a case report
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摘要: 笔者报道了1例行18F-氟脱氧葡萄糖(FDG)PET/CT显像的双肺多发结节性淀粉样变病例,分别从临床症状、影像学表现及病理诊断等方面分析了该病的特点,并通过文献复习加深了对肺淀粉样变的认知。结节性肺淀粉样变的发病率低,临床症状不典型,与常见的肺内肿瘤鉴别困难,临床鉴别肺结节时应考虑该病的可能。因此,18F-FDG PET/CT显像对双肺多发结节性淀粉样变病变范围的评估至关重要。Abstract: A case of double lung multiple nodular amyloidosis with 18F-fluorodeoxyglucose (FDG) PET/CT imaging was reported. The characteristics of the disease were analyzed from clinical symptoms, imaging manifestations and pathological diagnosis. The understanding of pulmonary amyloidosis was deepened through literature review. The incidence of pulmonary nodular amyloidosis is low, the clinical symptoms are atypical, and it is difficult to differentiate from common lung tumors. It is suggested that the possibility of pulmonary nodular amyloidosis should be considered in the differential diagnosis of pulmonary nodules. Therefore, 18F-FDG PET/CT imaging is very important to evaluate the extent of double lung multiple nodular amyloidosis.
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