-
1948年,Stout[1]首次报道恶性间叶瘤(malignant mesenchymoma,MM)是一种极为罕见的恶性肿瘤。MM好发生于四肢,也可发生于腹膜后、骨、胃肠道、胸膜等处[2],发生于肺部则较为罕见。我们通过分析本病例的18F-FDG PET/CT影像学表现并结合相关文献报道分析了MM的特点,以加深临床医师对肺MM影像学特征的认识。
18F-FDG PET/CT诊断肺恶性间叶瘤一例并文献复习
18F-FDG PET/CT diagnosis of lung malignant mesenchymoma: a case report and literature review
-
摘要: 恶性间叶瘤(MM)是一种由2种或2种以上不同类型的恶性间叶成分组成的软组织肉瘤,其发病率较低。笔者报道了1例通过18F-FDG PET/CT检查发现的发生于肺内的特殊MM病例,分别从临床症状、实验室检查、影像学表现并结合相关文献报道分析了MM的特点,以加深临床医师对肺MM的认识。Abstract: Malignant mesenchymoma (MM) is a a kind of soft tissue sarcoma composed of two or more different types of malignant mesenchymal components with a low incidence. The authors reported a special case of MM, which occurred in lung and was found by 18F-FDG PET/CT examination. The features of MM were analyzed from clinical symptoms, laboratory examinations, imaging findings and related literature reports, in order to deepen clinicians' understanding of lung MM.
-
Key words:
-
-
[1] Stout AP. Mesenchymoma, the mixed tumor of mesenchymal derivatives[J]. Ann Surg, 1948, 127(2): 278−290. DOI: 10.1097/00000658-194802000-00007. [2] Berzaczy D. Borderline and malignant mesenchymal tumors of the abdomen[J]. Radiologe, 2018, 58(1): 60−67. DOI: 10.1007/s00117-017-0335-7. [3] Chow LTC. Critical reappraisal of primary osseous composite sarcoma (malignant mesenchymoma)—analysis of four cases and literature review[J]. APMIS, 2016, 124(6): 487−499. DOI: 10.1111/apm.12540. [4] 颜海标, 付伟金, 韦羽, 等. 肾恶性间叶瘤的诊断与治疗(附3例报告并文献复习)[J]. 临床泌尿外科杂志, 2010, 25(9): 656−657, 660. DOI: 10.3969/j.issn.1001-1420.2010.09.005.
Yan HB, Fu WJ, Wei Y, et al. Diagnosis and treatment of kidney malignant mesenchymomas (report of 3 cases and literature review)[J]. J Clin Urology, 2010, 25(9): 656−657, 660. DOI: 10.3969/j.issn.1001-1420.2010.09.005.[5] 潘德利. 腹膜后恶性间叶瘤的CT诊断[J]. 实用心脑肺血管病杂志, 2009, 17(4): 313−314. DOI: 10.3969/j.issn.1008-5971.2009.04.045.
Pan DL. CT diagnosis of retroperitoneal malignant mesenchymal tumor[J]. Pract J Cardiac Cerebral Pneumal Vascular Dis, 2009, 17(4): 313−314. DOI: 10.3969/j.issn.1008-5971.2009.04.045.[6] Yang ZC, Yang XD, Lu XQ, et al. Primary malignant mesenchymoma of bladder: case report and review of the literature[J]. Medicine (Baltimore), 2017, 96(32): e7579. DOI: 10.1097/MD.0000000000007579. [7] Deshmukh AV, Shivkumar VB, Gangane NM. A rare case of primary malignant mesenchymoma arising from submandibular salivary gland[J]. Oman Med J, 2020, 35(6): e209. DOI: 10.5001/omj.2020.98. [8] 郭国栋, 黄海建, 陈小岩. 恶性外胚叶间叶瘤1例临床病理观察并文献复习[J]. 临床与实验病理学杂志, 2017, 33(9): 1043−1045. DOI: 10.13315/j.cnki.cjcep.2017.09.027.
Guo GD, Huang HJ, Chen XY. Malignant ectodermal mesenchymal tumor: a case report and literature review[J]. J Clin Exp Pathol, 2017, 33(9): 1043−1045. DOI: 10.13315/j.cnki.cjcep.2017.09.027.[9] Tsuchiya M, Masui T, Otsuki Y, et al. 18F-FDG PET/CT findings of mesenchymal chondrosarcoma of the orbit[J]. Clin Nucl Med, 2018, 43(2): e43−e45. DOI: 10.1097/RLU.0000000000001915. [10] Broski SM, Folpe AL, Wenger DE. Imaging features of phosphaturic mesenchymal tumors[J]. Skeletal Radiol, 2019, 48(1): 119−127. DOI: 10.1007/s00256-018-3014-5. [11] Koksal D, Demirag F, Bayiz H, et al. The correlation of SUVmax with pathological characteristics of primary tumor and the value of tumor/ lymph node SUVmax ratio for predicting metastasis to lymph nodes in resected NSCLC patients[J/OL]. J Cardiothorac Surg, 2013, 8: 63[2021-01-04]. https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/1749-8090-8-63. DOI: 10.1186/1749-8090-8-63. [12] Adachi T, Oda Y, Sakamoto A, et al. Prognostic factors in the so-called malignant mesenchymoma: a clinicopathological and immunohistochemical analysis[J]. Oncol Rep, 2003, 10(4): 803−811. DOI: 10.3892/or.10.4.803.