Abstract: In China, the incidence and mortality of prostate cancer (PCa) are increasing gradually, and the early diagnosis and accurate staging of PCa patients is still a major problem. Therefore, most patients have been diagnosed with advanced stage, leading to poor survival prognosis. MRI, CT, PET/CT and other imaging examinations are currently the main means for the diagnosis and staging of PCa, but these methods have also been found to have certain limitations, so they are constantly being explored and optimized. In particular, the application of various imaging agents in PET/CT has greatly improved the diagnostic sensitivity and specificity of PCa and shows a good prospect in the early diagnosis, timely treatment, clinical staging and prognosis evaluation of PCa. In this paper, these common imaging methods and PET/CT imaging agents are discussed; their advantages, disadvantages and new application progress are summarized, hoping to provide references to clinicians.