Abstract: Lymphoma is a malignant tumor of the hematological system that originates from different sites of the body and has a variety of pathological types. Maximum standardized uptake value, a traditionally used evaluation index, can reflect the maximum metabolic activity in tumor tissues, and which is the most widely studied metabolic parameter in clinical research at present. PET volume computed assisted reading (VCAR) software can measure and analyze the lymphoma lesions and automatically calculate the metabolic evaluation indexes of the lesions, including the peak SUV normalized by lean body mass, metabolic tumor volume, total lesion glycolysis, etc. There are many pathological subtypes of lymphoma, and the above metabolic evaluation parameters have different diagnosis and efficacy evaluation efficiency for different types of lymphoma. Therefore, the author intends to review recent advances in the effective prediction of the diagnostic and therapeutic effect of lymphoma based on the metabolic assessment of ¹⁸F-fluorodeoxyglucose PET VCAR software.