术前18F-FDG PET/CT显像代谢参数在非小细胞肺癌患者预后评估中的应用进展

Application progress of preoperative 18F-FDG PET/CT imaging metabolic parameters in the prognostic evaluation of patients with non-small cell lung cancer

  • 摘要: 肺癌是目前世界上最常见的癌症之一,在所有的恶性肿瘤中,肺癌的病死率高居榜首,而非小细胞肺癌(NSCLC)约占所有肺癌的85%。18F-氟脱氧葡萄糖(FDG)PET/CT作为一种从分子水平反映肿瘤细胞代谢状态的功能显像方法,已成为NSCLC诊断、分期和疗效评价的重要工具。18F-FDG PET/CT可检测出常规CT遗漏的其他病变部位,在肺癌患者的手术切除预后方面起着越来越重要的作用。笔者就18F-FDG PET/CT相关代谢参数在预测可手术切除NSCLC患者预后方面的应用进展进行综述。

     

    Abstract: Lung cancer is one of the commonest cancers in the world. Among all malignant tumors, lung cancer has the highest fatality rate, while non-small cell lung cancer (NSCLC) accounts for about 85% of all lung cancer. As a functional imaging method that reflects the metabolic status of tumor cells at the molecular level, 18F-fluorodeoxyglucose (FDG) PET/CT has become an important tool for diagnosis, staging and efficacy evaluation of NSCLC. 18F-FDG PET/CT plays an increasingly important role in the prognosis of the patients with surgically resected NSCLC, because it can detect lesions left out by conventional CT. This paper reviews the application progress of 18F-FDG PET/CT related metabolic parameters in predicting the prognosis of resectable NSCLC.

     

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