Abstract: Diffusion kurtosis imaging (DKI) is the extension and supplement of diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI). DKI further reveals the Non-Gaussian diffusion model of water molecule movement in organisms. DKI is more suitable for reflecting the micro-environment of human body and provides more accurate, real, and rich organizational microstructure information compared with DWI and DTI technologies. DKI has been gradually applied to the study of diseases in various systems, particularly the nervous system. This technology has achieved remarkable results and shows good clinical value. DKI can reflect microscopic information and has great application prospects. Currently, this technology is contributing to the increase in the number of research works on the liver. This article reviews the application of DKI to the study of liver diseases.