2004 Vol. 28, No. 5
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2004, 28(5): 193-196.
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Abstract:
The value of 18F-FDG imaging with dual-head gamma camera has been demonstrated by a large number of clinical studies. For 18F-FDG coincidence imaging, however, effective factors are various from the patient's preparation to the results interpreted. The purpose of this paper was to outline the quality assurance procedures for this kind of imaging. Six items were included, such as acceptance testing and daily quality control of the imaging instruments, patients interviewing, 18F-FDG injection, data acquisition, data processing and results interpreter. After reading this paper, the readers should be awaked to the careful consideration of executing a coincidence imaging.
The value of 18F-FDG imaging with dual-head gamma camera has been demonstrated by a large number of clinical studies. For 18F-FDG coincidence imaging, however, effective factors are various from the patient's preparation to the results interpreted. The purpose of this paper was to outline the quality assurance procedures for this kind of imaging. Six items were included, such as acceptance testing and daily quality control of the imaging instruments, patients interviewing, 18F-FDG injection, data acquisition, data processing and results interpreter. After reading this paper, the readers should be awaked to the careful consideration of executing a coincidence imaging.
2004, 28(5): 197-199.
Abstract:
Tg (thyroglobulin) is an established serum tumour marker in the follow-up of differentiated thyroid cancer. However, serum Tg measurement remains one of the most difficult biochemical tests for a laboratory to maintain to a high level of precision and reliability. TgAb (Tg antibody) interference is the most serious specificity problem affecting serum Tg measurement, regardless of the assay. This review presented an overview of the critical problems that should he taken into account in the measurements and clinical evaluation of serum Tg and TgAb in differentiated thyroid cancer.
Tg (thyroglobulin) is an established serum tumour marker in the follow-up of differentiated thyroid cancer. However, serum Tg measurement remains one of the most difficult biochemical tests for a laboratory to maintain to a high level of precision and reliability. TgAb (Tg antibody) interference is the most serious specificity problem affecting serum Tg measurement, regardless of the assay. This review presented an overview of the critical problems that should he taken into account in the measurements and clinical evaluation of serum Tg and TgAb in differentiated thyroid cancer.
2004, 28(5): 199-202.
Abstract:
All kinds of nuclein scanning includeing SPECT、PET and PET/CT in liver carcinoma have a definite clinical impact on diagnosis,differential diagnosis between malignant and benign tumor,and evaluation of differentiation of tumor cell. Especially fluorine-18-deoxyglucose PET and carbon-11-acetate PET play a more important role in assessement of differentiation of liver carcinoma than CT and MRI. Combined with the examinations of morphology, PET/CT will provide better imaging effect for lesion' localization and characterization.
All kinds of nuclein scanning includeing SPECT、PET and PET/CT in liver carcinoma have a definite clinical impact on diagnosis,differential diagnosis between malignant and benign tumor,and evaluation of differentiation of tumor cell. Especially fluorine-18-deoxyglucose PET and carbon-11-acetate PET play a more important role in assessement of differentiation of liver carcinoma than CT and MRI. Combined with the examinations of morphology, PET/CT will provide better imaging effect for lesion' localization and characterization.
2004, 28(5): 203-206.
Abstract:
As a tumor imaging agent, 99Tcm-MIBI(99Tcm-sestamibi) scintigaphy has high sensitivity, specifity and accuracy in diagnosis of head and neck cancer. It can also be used to detect cervical lymph nodes involved and assess osseous tumor spread. 99Tcm-MIBI scintigraphy can provide useful in-formation of diagnosis and staging of head and neck cancer.
As a tumor imaging agent, 99Tcm-MIBI(99Tcm-sestamibi) scintigaphy has high sensitivity, specifity and accuracy in diagnosis of head and neck cancer. It can also be used to detect cervical lymph nodes involved and assess osseous tumor spread. 99Tcm-MIBI scintigraphy can provide useful in-formation of diagnosis and staging of head and neck cancer.
2004, 28(5): 206-209.
Abstract:
Somatostatin analogues, such as octreotide, depreotide and so on, having long-time and high affinity with somatostatin receptors(SSTR) and labeled by radionuclides, can be used in SSTR scintigraphy and treatment of tumors expressing SSTR. Moreover, Lymphoma express SSTR(SSTR2 and SSTR3). A series of clinical and experimental results showed SSTR scintigraphy is an interesting way to evaluate the diagnosis, staging, treatment and prognosis of lymphoma, and a supplemental tool of diagnosing and judging lymphoma with conventional X-rays imaging, 67Ga and PET. Whereas, the application of radionuclide-labeled somatostatin analogues in treatment of lymphoma should be cautiously performed. Recently it is a concerned question how the patients suffering from lymphoma can have the most profits and the least side-effects from the treatment of radionuclide-labeled somatostatin analogues.
Somatostatin analogues, such as octreotide, depreotide and so on, having long-time and high affinity with somatostatin receptors(SSTR) and labeled by radionuclides, can be used in SSTR scintigraphy and treatment of tumors expressing SSTR. Moreover, Lymphoma express SSTR(SSTR2 and SSTR3). A series of clinical and experimental results showed SSTR scintigraphy is an interesting way to evaluate the diagnosis, staging, treatment and prognosis of lymphoma, and a supplemental tool of diagnosing and judging lymphoma with conventional X-rays imaging, 67Ga and PET. Whereas, the application of radionuclide-labeled somatostatin analogues in treatment of lymphoma should be cautiously performed. Recently it is a concerned question how the patients suffering from lymphoma can have the most profits and the least side-effects from the treatment of radionuclide-labeled somatostatin analogues.
2004, 28(5): 210-212.
Abstract:
18F-FDG PET is an important imaging technique in the stage of patients with lymphoma and more sensitive and accurate than gallium scintigraphy. Persistently positive PET imaging during and after chemotherapy have a high sensitivity for predicting subsequent relapse. A negative PET imaging at the end of therapy provides favorable prognostic information. Compared to other conventional imaging modalities, 18F-FDG PET significantlyimproves the accuracy of imaging tumors in initial staging, and monitoring of therapy response of lymphoma.
18F-FDG PET is an important imaging technique in the stage of patients with lymphoma and more sensitive and accurate than gallium scintigraphy. Persistently positive PET imaging during and after chemotherapy have a high sensitivity for predicting subsequent relapse. A negative PET imaging at the end of therapy provides favorable prognostic information. Compared to other conventional imaging modalities, 18F-FDG PET significantlyimproves the accuracy of imaging tumors in initial staging, and monitoring of therapy response of lymphoma.
2004, 28(5): 213-216.
Abstract:
Adrenomedullin is a regulatory peptide involved in several physiological processes.Recently, adrenomedullin has been proved that it is widely expressed in tumor and may have a significiant role in tumor progression and differentiation by stimulating mitogenic activities, inhibiting immune response, inhibiting apoptosis and enhancing angiogenesis.
Adrenomedullin is a regulatory peptide involved in several physiological processes.Recently, adrenomedullin has been proved that it is widely expressed in tumor and may have a significiant role in tumor progression and differentiation by stimulating mitogenic activities, inhibiting immune response, inhibiting apoptosis and enhancing angiogenesis.
2004, 28(5): 216-219.
Abstract:
Cardiac markers are presently a hot topic of studying. They now have a major role for diagnosis myocardial damage and acute myocardial infarction. It is important to search and screen a sensitive, specific and early markers of myocardial damage. The quick, accurate and sensitive assay methodology is still an important research in this field. Therefore rapid muli-analyte point-of-care tests have facilitated the use of cardiac markers for clinical management and guidance of therapy.
Cardiac markers are presently a hot topic of studying. They now have a major role for diagnosis myocardial damage and acute myocardial infarction. It is important to search and screen a sensitive, specific and early markers of myocardial damage. The quick, accurate and sensitive assay methodology is still an important research in this field. Therefore rapid muli-analyte point-of-care tests have facilitated the use of cardiac markers for clinical management and guidance of therapy.
2004, 28(5): 220-221,229.
Abstract:
The theory of tumor markers and chemiluminescent immunoassay was introduced briefly. The recent application of chemiluminescent immunoassay in evaluation of tumor markers was reviewed, and the development of its application in evaluation of tumor markers in future was also viewed.
The theory of tumor markers and chemiluminescent immunoassay was introduced briefly. The recent application of chemiluminescent immunoassay in evaluation of tumor markers was reviewed, and the development of its application in evaluation of tumor markers in future was also viewed.
2004, 28(5): 222-225.
Abstract:
There is growing concern regarding the radiation dose delivered during interventional procedures, particularly in view of the increasing frequency and complexity of these techniques. Studies have focused on three fields:the radiation dose levels currently encountered in interventional procedures, the consequent risk to operators and patients and protection methods.
There is growing concern regarding the radiation dose delivered during interventional procedures, particularly in view of the increasing frequency and complexity of these techniques. Studies have focused on three fields:the radiation dose levels currently encountered in interventional procedures, the consequent risk to operators and patients and protection methods.
2004, 28(5): 226-229.
Abstract:
A widely accepted therapy was 131I for patients with thyroid disease. However, the patients who had received 131I therapy may turn into a "radiant source", the individuals surrounding the patients undergone such treatment could unavoidably exposed to the radiation. The progression on the regulation or standard which relevant international organizations and departments of various countries, and the measurement and calculation of the 131I radiation dose, was used to guide the clinical practice work and determined to give the treatment of whether inpatients or outpatients, made the individuals avoid accepting unnecessary radiation exposure in the article.
A widely accepted therapy was 131I for patients with thyroid disease. However, the patients who had received 131I therapy may turn into a "radiant source", the individuals surrounding the patients undergone such treatment could unavoidably exposed to the radiation. The progression on the regulation or standard which relevant international organizations and departments of various countries, and the measurement and calculation of the 131I radiation dose, was used to guide the clinical practice work and determined to give the treatment of whether inpatients or outpatients, made the individuals avoid accepting unnecessary radiation exposure in the article.
2004, 28(5): 230-233.
Abstract:
Microphysics mechanism of radial particles acting with body tissue was analyzed. The radial particle microdosimetry is considered to be the important tool in the research of radial biological effects. The feasibility of trace structure research method was affirmed in this research. Some physics parameters were calculated accurately by using code ESLOW3.1 and MOCA15.
Microphysics mechanism of radial particles acting with body tissue was analyzed. The radial particle microdosimetry is considered to be the important tool in the research of radial biological effects. The feasibility of trace structure research method was affirmed in this research. Some physics parameters were calculated accurately by using code ESLOW3.1 and MOCA15.
2004, 28(5): 234-236.
Abstract:
With the increased awareness of the contribution of indirect and delayed effects (such as mutation, genomic instability) to cellular outcomes after low-dose exposures, and the availability of tools (such as the microbeam and advanced cell culture systems), many new discoveries about radiation-induced bystander effect has been achieved in the past decade. Evidence accumulated has indicated that radiation-induced bystander effect is regulated by special genes, and mediated by intercellual signal transmission pathway.
With the increased awareness of the contribution of indirect and delayed effects (such as mutation, genomic instability) to cellular outcomes after low-dose exposures, and the availability of tools (such as the microbeam and advanced cell culture systems), many new discoveries about radiation-induced bystander effect has been achieved in the past decade. Evidence accumulated has indicated that radiation-induced bystander effect is regulated by special genes, and mediated by intercellual signal transmission pathway.
2004, 28(5): 237-240.
Abstract:
Infrared radiation has hot effect and can make molecule of organism produce the effect of resonance and absorbtion. It can ameliorate local blood circulation, relieve spasm and pain and adjuvantly treat lats of disease after radiating human body. There is good application prospect, especially at the therapy of tumor. The technique and device of infrared does not damage human and does not pollute environment. It can diplay the screenage on body's organ metabolism function, while other diagnosis apparatus can not do these. It develops a new domain of medical screenage technology on functiology. It provids means and technologe of screenage dipiay for disease diagnosis and medicine research. It piaies an important role in medical practice and summary.
Infrared radiation has hot effect and can make molecule of organism produce the effect of resonance and absorbtion. It can ameliorate local blood circulation, relieve spasm and pain and adjuvantly treat lats of disease after radiating human body. There is good application prospect, especially at the therapy of tumor. The technique and device of infrared does not damage human and does not pollute environment. It can diplay the screenage on body's organ metabolism function, while other diagnosis apparatus can not do these. It develops a new domain of medical screenage technology on functiology. It provids means and technologe of screenage dipiay for disease diagnosis and medicine research. It piaies an important role in medical practice and summary.
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