Application of carbon-11 radiopharmaceuticals in PET-CT for tumors

¹⁸F-fluorodeoxyglucose(¹⁸F-FDG) was most wildly used radiopharmaxeuticals for tumors. It wasn't suitable for some malignant tumors because of it's normal biodistribution. We review some ¹¹C labeled radiopharmaceuticals, including ¹¹C-methionine, ¹¹C-choline and ¹¹C-acetate, for primary diagnosis and staging with brain tumors, head and neck cancer, lung cancer, liver tumors, gynecologic tumors, prostate cancer, bladder cancer, bone and soft tissue tumors, and the monitor value for radiotherapy. The ¹¹C labeled radiopharmaceuticals were very important complement of ¹⁸F-FDG.