Dosimetric advancement of high-dose-rate after-loading 192Ir source
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Abstract
High-dose-rate (HDR) 192Ir source is a nuclide commonly used in the brachytherapy system. The basic dosimetry data of the near source area is usually measured by pin ion chambers or TLD techniques, but these methods have a lower spatial resolution than Electron spin resonance (ESR) dosimetry which has a spatial resolution of 156μm, and the Monte Carlo photon transport simulations are taken as the golden standard of those measures. The precision in two-dimensional dose distribution measured by GafChromic film is reported to be 1.0%. In vivo dosimetry using TLD during HDR intracavitary after-loading brachytherapy is a good predictor of late rectal complications. The accuracy of magnetic resonance imaging (MRI) Fricke-gel dosimetry for three-dimensional dose distribution is about 2.5% with a spatial resolution of 1.56mm. The optical computed tomography polymer gel dosimetry has a unique advance than MRI gel dosimetry.
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