Application of study in microdosimetry with the frozen sectioning microaut-oradiogtraphy technique

Objective To survey the distribution of radionuclide in cell level by frozen sectioning microautoradiogtraphy technique. Methods The article will describe the micro distribution of ¹³¹I and ^99mTc using autoradiogtraphy and frozen sectioning technique. Results To describe the relationship between argent grain density and nuclide radioactivity a regression curve of ^99mTc and ¹³¹I was depicted and the R value calculated to be 0.9915 and 0.9963 respectively, The scale coeflqcient of argent grain were 1,59×10^-4Bq and 6.48×10^-5Bq respectively. Conclusion The distribution of radiomedicament ¹³¹I and ^99mTc at cellular level is nonunidoem.