The study progress of stereotatic radiosurgery radlobiological action on the normal brain tissue

The stereotatic radionsurgery(SRS) therapeutic tool mainly include gamma knife and X-knife, high energic ray was applicated to the intracranial target lesion and eanse radiological injury, with minimal radiation injury to the surrounding tissue because of the sharp dose gradient. Because of efficiently controling disease and no suffering from operation, SRS has more safety. But when the SRS irradion convey to the target, the peripheral normal brain tissue also have radiobiological reaction. This article reviewed the radiobiological effect of SRS treatment on the normal brain tissue.