The prognostics analysis of whole nervous system irradiation combined local dose accumulating for patients with intracranial germinoma

Objective To analyze the result of whole nervous system and local site irradiation for 46 patients with intracranial germinoma. Methods Long term follow-up is exerted for these patients beween Octomber, 1995 and Octomber, 2006. The results is analysed. Results 5-year and 10-year survival rate is 93.8% and 82.6% respectively. No prognostic factors are effective statistically. Conclusion Whole central nervous irradiation for treatment of intracranial germinoma is essential. The results of the patients are satisfactory. Long-term radition brain injury is rare.