Tumor radiosensitivity and apoptosis

ZHU Guang-xu, Wang Xiao-hua. Tumor radiosensitivity and apoptosis[J]. Int J Radiat Med Nucl Med, 2000, 24(2): 78-82.

Citation:

ZHU Guang-xu, Wang Xiao-hua. Tumor radiosensitivity and apoptosis[J]. Int J Radiat Med Nucl Med, 2000, 24(2): 78-82.

Citation:

ZHU Guang-xu, Wang Xiao-hua. Tumor radiosensitivity and apoptosis[J]. Int J Radiat Med Nucl Med, 2000, 24(2): 78-82.

Abstract

Radiosensitivity is a complex phenomenon in tumor cells and there exist special biological effects in different types of tissues' cells in inadiation-induced cell responses. Tumor radiosentivity is tightly connected with irradiation-induced apoptosis and is regulated by many protein products of apoptosis-related genes such as p53 and related proteins, Bcl-2 gene family proteins, Fas and sphingomyelin/ceramide-mediated signalling pathways and caspases cascade etc.

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