Clinical application of 11C-acetate PET metabolism imaging
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Abstract
18F-fluorodeoxyglueose (18F-FDG) is the most widely used PET agent for imaging tumors. However, 18F-FDG PET showed a relatively high false positive rate when it is used to differentia the malignant and benign lesions. 11C-aeetate metabolie PET may overcome some limitations of 18F-FDG PET and has elinieal potentials. It has demonstrated advantages over 18F-FDG PET in the tumors such as prostate cancer, hepatocellular carcinoma. Because of the metabolie characteristics of 11C-acetate, it may be used to assess myoeardial viability, blood flow and peffusion.
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