Cytokines combination in acute radition injury management

Cytokine-based treatment was well applied to manage acute radiation injury in recent years.Unfortunately, efficacy of single cytokine was reduced because of multiple organs severe injury caused by high dose irradiation. It is the rationale for cytokines combination. Anti-radiation efficacy of cytokines combination were reviewed, especially hematopoietic growth factors and antiappoptic cytokines combined in acute radiation injury management were documented. Emergency cytokines combination would be an alternative for acute radiation injury treatment.