Plasminogen activator and its assay of the activity

Plasminogen activators (PA) are specific proteolytic enzymes Which convert the inactive proenzymen to plasmin.The plasmin formed is a potent and nonpecific protease which cleaves blood fabrin clots into soluble polypeplide. This article describes some biochemical chatacteristic of the different compotents of the plsminogen activator system,current methods for assay of the activity of the PA.The potential application of PA as diagnostic tools in diseases of the thrombi.