Lung cancer radionuclide imaging targeting at vascular endothelial growth factor and its receptor

The lung cancer must establish an angiogenesis to grow, to invade, and to metastasize, in which vascular endothelial factor (VEGF) is the most functional and special adjusting factor and play an important role. So anticancer by inhibiting the expression, activity and signal conduction of VEGF become one of the new and effective methods. Meanwhile, radionuclide imaging targeting at VEGF and its receptor not only can display the angiogenesis of lung cancer, but also has profound meaning in the early diagnosis, the correct staging, and the prognosis of lung cancer.