Curent developments in the study of effects of irradiation on bone marrow haematopoietic microenvironment

Hemotopoiesis completely depends on the regulation of the microenvironment. It has been indicated in the early and recent study the long-term effects of radiation on bone marrow microenvironment. It has been found in some experiments that after radiation the colony stimulating activity, the expression of growth factor (GMCSF) and adhesion molecule(V CAM-1) of the stroma cells was elevated.