Analysis of abnormal liver uptake of ⁹⁹Tc^m-MDP in bone scan

Objective To analyze the possible causes of liver uptake in ⁹⁹Tc^m-MDP bone scan.

Methods A retrospective analysis was performed on 20 cases of abnormal liver uptake in bone scan in our hospital from January 2013 to July 2015. The results were compared with other imaging examinations and/or pathological findings and laboratory examinations.

Results Twenty patients were found to have abnormal liver uptake of the imaging agent, including 3 cases with primary liver injury, 17 cases with secondary liver injury, which include 1 case with multiple myeloma and 7 cases with liver metastasis(5 cases with colorectal cancer, 1 with from hepatocellular carcinoma, 1 case with lung cancer), and 1 case of liver uptake after iron treatment. Conclusion Abnormal liver uptake of ⁹⁹Tc^m-MDP in bone imaging is associated with several reasons; barring technical reasons, we should be alert to the liver injury caused by various reasons to provide reference for patients prior to clinical intervention.