Value of ¹⁸F-FDG PET/CT on diagnosis of Hodgkin lymphoma recurrence using Deauville criterion

Objective To investigate the diagnostic value of ¹⁸F-FDG PET/CT on Hodgkin lymphoma(HL) recurrence according to Deauville criterion.

Methods Retrospective analysis was performed on 24 HL cases for a period of 5-27 months after treatment. These patients were clinically suspected of recurrence.

Results of ¹⁸F-FDG PET/CT imaging according to Deauville criterion, lymph node biopsies, and(or) bone marrow biopsy pathology were analyzed and compared.

Results Seventeen cases of recurrence were confirmed by pathologic findings. Three cases of lymph node reactive hyperplasia, 1 case of lung cancer with mediastinal lymph node metastasis, and 3 cases without recurrence were recorded. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 100%, 50%, 85%, 100%, and 87% for ¹⁸F-FDG PET/CT on HL recurrence diagnosis.

Conclusion ¹⁸F-FDG PET/CT is of important clinical value on the diagnosis of HL recurrence according to the standard of Deauville criterion.