Meiting Fan, Yun Ma, Shuya He. Research progress and prediction on pleiotropic protein PprA from Deinococcus radiodurans[J]. Int J Radiat Med Nucl Med, 2015, 39(2): 149-153. DOI: 10.3760/cma.j.issn.1673-4114.2015.02.010
Citation: Meiting Fan, Yun Ma, Shuya He. Research progress and prediction on pleiotropic protein PprA from Deinococcus radiodurans[J]. Int J Radiat Med Nucl Med, 2015, 39(2): 149-153. DOI: 10.3760/cma.j.issn.1673-4114.2015.02.010

Research progress and prediction on pleiotropic protein PprA from Deinococcus radiodurans

  • Deinococcus radiodurans(DR) is a model organism to study radiation resistance. PprA protein(pleiotropic protein promoting DNA repair) is a unique, pleiotropic protein promoting DNA repair in DR. This article reviewed its possible function in DNA damage repairing, maintenance of genome stability and other aspects. Furthermore, we analyze its domain of pprA genes and by bioinformatics and predict interaction protein with PprA protein, in order to predict its function and understand the mechanisms and pathways it plays.
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