Wei LONG, Jin JIN, Jia-li BAI, Wei-min GONG, Xiu SHEN, Ze-wei ZHOU. A preliminary study on anti-radiation effects of two cinnamic paeonol ester compounds[J]. Int J Radiat Med Nucl Med, 2013, 37(3): 143-145, 159. DOI: 10.3760/cma.j.issn.1673-4114.2013.03.004
Citation: Wei LONG, Jin JIN, Jia-li BAI, Wei-min GONG, Xiu SHEN, Ze-wei ZHOU. A preliminary study on anti-radiation effects of two cinnamic paeonol ester compounds[J]. Int J Radiat Med Nucl Med, 2013, 37(3): 143-145, 159. DOI: 10.3760/cma.j.issn.1673-4114.2013.03.004
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A preliminary study on anti-radiation effects of two cinnamic paeonol ester compounds

    Abstract
  • Objective To study the anti-radiation effect of two clinnamic paeonol ester compounds.
    Method The index like white blood cell count, platelet count, bone marrow nucleated cells count, DNA and other organ index on ICR mice were observed to investigate the anti-radiation effect of the two compounds in high, medial and low dosages.
    Results Compared to the control group, the increase of DNA content in marrow, the number of splenic nodules, splenic index and thymus index have been observed in group of 4-methyl cinnamic acid paeonol ester and 4-fluoro cinnamic acid paeonol ester.
    Conclusion 4-methyl cinnamic acid paeonol ester and 4-fluoro cinnamic acid paeonol ester both have the protection effect against radiation damage.
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