Xiu SHEN, Xiao-qiu LIU, Ze-wei ZHOU, Fu-jun YANG, Xiao-dong ZHANG, Wei LONG, Hao WANG, Ge HONG, Wen-qing XU. Biological characteristic of Kunming-hairless mice[J]. Int J Radiat Med Nucl Med, 2013, 37(2): 74-76, 87. DOI: 10.3760/cma.j.issn.1673-4114.2013.02.003
Citation: Xiu SHEN, Xiao-qiu LIU, Ze-wei ZHOU, Fu-jun YANG, Xiao-dong ZHANG, Wei LONG, Hao WANG, Ge HONG, Wen-qing XU. Biological characteristic of Kunming-hairless mice[J]. Int J Radiat Med Nucl Med, 2013, 37(2): 74-76, 87. DOI: 10.3760/cma.j.issn.1673-4114.2013.02.003
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Biological characteristic of Kunming-hairless mice

    Abstract
  • Objective To observe the biological parameters of the new strain Kunming-hairless mice on the condition of normal, irradiation and tumor-implanting.
    Methods ① The physiological parameters of normal Kunming mice and normal Kunming-hairless mice were observed. ②After being inoculated with hepatic carcinoma H22, leukemia L1210, tumor growth of the two kinds of mice was observed. ③White blood cell count, thymus index and spleen index parameters were observed after irradiation by 137Cs γ-ray.
    Results The differences of normal parameters between Kunming mice and Kunming-hairless mice were not significant, but the immune parameter-thymuses of Kunming-hairless mice were smaller than that of Kunming mice, tumors growth after implantation were quite well in both strain Kunming and Kunming-hairless mice.
    Conclusion As pure strain animal, Kunming-hairless mice possesses biological traits of Kunming mice, it can be applied to the sciences experiment.
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