A preliminary study on clinical value of ¹⁸F-FDG PET-CT in evaluation of efficacy of Hodgkin lymphoma

Objective To explore the clinical value of ¹⁸F-FDG PET-CT in the evaluation of efficacy of Hodgkin lymphoma(HL).

Methods Thirty-one cases of post-treatment patients with HL were studied retrospectively. ¹⁸F-FDG PET-CT images after chemotherapy were compared with CT post-therapy results. The final diagnosis was based on pathology or clinical follow-ups.

Results ① A total of 94 malignant lesions and 51 benign lesions were found in 31 patients in the study. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of ¹⁸F-FDG PET-CT in the evaluation of efficacy of HL were 97.87%, 94.12%, 96.84%, 96.00% and 96.55% respectively, which were significantly superior to CT examination alone(χ²=9.83, 13.49, 11.50, 11.69, 22.58, all P < 0.05). ②According to the results of PET-CT, therapeutic schedules of 16 cases(51.61%)had been changed.

Conclusion ¹⁸F-FDG PET-CT is an effective method in the evaluation of efficacy of HL.